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Title: A Computational Model for Cell Survival Death Using VHDL and MATLAB Simulator
Authors: Jain, Shruti
Naik, Pradeep K.
Sharma, Rohit
Keywords: Tumor Necrosis Factor-α
Epidermal Growth Factor
Issue Date: 2009
Publisher: Jaypee University of Information Technology, Solan, H.P.
Abstract: A well-structured and controlled design methodology, along with a supporting hierarchical design system, has been developed to optimally support the development effort on several programs requiring gate array and semi custom Very Large Scale Integration (VLSI) design. In this paper, we will present an application of VLSI in System Biology. This work examines signaling networks that control the survival decision treated with combinations of three primary signals the pro death cytokine, tumor necrosis factor-α (TNF), and the pro survival growth factors, epidermal growth factor (EGF) and insulin. We have made model by taking three inputs, than made the truth table, Boolean equation and than implement the equation using Very High Speed Integrated Circuit Hardware Description Language (VHDL) (Xilinx Tool) and MATLAB simulator.
Description: Digest Journal of Nanomaterials and Biostructures Vol. 4, No. 4, December 2009, p. 863 – 879
Appears in Collections:Journal Articles

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