Design and Evaluation of Molecules for Parkinsons Disease

Abstract

Parkinson’s disease is a chronic, progressive disorder of the nervous system that causes the malfunction and death of neurons in the brain. Parkinson’s disease (PD) typically starts with a minor tremor and develops gradually, eventually causing stiffness throughout the body and slowing movement .An accelerating ache of the afraid arrangement apparent by tremor, ablebodied rigidity, and slow movement, chiefly affecting middle-aged and aged people. It is associated with decline of the basal ganglia of the academician and absence of the neurotransmitter dopamine. Some neurons aftermath dopamine, a actinic that sends letters to the allotment of the academician that controls movement, and as these neurons die from Parkinson’s disease, the bulk of dopamine decreases and movement is affected. After diagnosis, treatments can advice abate symptoms, but there is no cure. Acknowledgment to assertive toxins has acquired Parkinson’s affects in attenuate affairs. Other still-unidentified ecology factors may as well could cause PD. Parkinson’s disease has no cure but its progression can be slowed down with the help of chemical L-DOPA( Levodopa).