Please use this identifier to cite or link to this item: http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9382
Title: Sodium Dodecyl Sulphate-Supported Nanocomposite as Drug Carrier System for Controlled Delivery of Ondansetron
Authors: Sharma, Gaurav
Naushad, Mu.
Thakur, Bharti
Kumar, Amit
Negi, Poonam
Saini, Reena
Chahal, Anterpreet
Kumar, Ashok
Stadler, Florian J.
Aqil, U.M.H.
Keywords: Sodium dodecyl sulphate
Nanocomposite
Drug delivery
Ondansetron
Issue Date: 2018
Publisher: Jaypee University of Information Technology, Solan, H.P.
Abstract: Sodium dodecyl sulphate-supported iron silicophosphate (SDS/FeSP) nanocomposite was successfully fabricated by the co-precipitationmethod. The SDS/FeSP nanocompositewas investigated as a drug carrier for ondansetron. The cumulative drug release of ondansetron was observed at various pH values for different time intervals, i.e., from 20 min to 48 h. A ranking of the drug release was observed at different pHs; pH 2.2 > saline (pH 5.5) > pH 7.4 > pH 9.4 > distilled water. Maximum release of encapsulated drug was found to be about 45.38% at pH 2.2. The cell viability tests of SDS/FeSP nanocomposite concluded that SDS/FeSP nanocomposite was non-cytotoxic in nature.
URI: http://ir.juit.ac.in:8080/jspui/jspui/handle/123456789/9382
Appears in Collections:Journal Articles



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